Seminars in Pediatric Neurology
Volume 14, Issue 4 , Pages 173-180, December 2007

Cognitive and Magnetic Resonance Volumetric Abnormalities in New-Onset Pediatric Epilepsy

  • Bruce P. Hermann, PhD

      Affiliations

    • Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, WI.
    • Corresponding Author InformationAddress reprint requests to Bruce Hermann, PhD, Department of Neurology, University of Wisconsin, 600 N Highland Ave, Madison WI 53792.
  • ,
  • Jana Jones, PhD

      Affiliations

    • Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, WI.
  • ,
  • Raj Sheth, MD

      Affiliations

    • Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, WI.
  • ,
  • Michael Seidenberg, PhD

      Affiliations

    • Department of Psychology, Rosalind Franklin University of Medicine and Science, North Chicago, IL.

This paper addresses the issue of cognitive morbidity and abnormalities in quantitative MR volumetric in children with new and recent onset idiopathic epilepsy. The available literature suggests that mild diffuse cognitive problems are evident in children with new onset epilepsy in the context of intact whole brain and lobar volumetrics. Subsets of children can be identified with salient academic and volumetric abnormalities. These findings represent the baseline upon which any subsequent effects of chronic epilepsy may accrue.

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 Supported by NIH grant no. RO1 44351.

PII: S1071-9091(07)00056-3

doi:10.1016/j.spen.2007.08.003

Seminars in Pediatric Neurology
Volume 14, Issue 4 , Pages 173-180, December 2007